Kristiina M. Huttunen

Design, Synthesis and Brain Uptake of LAT1-Targeted Amino Acid Prodrugs of Dopamine

Lauri Peura, Kalle Malmioja, Kristiina M. Huttunen et al. · Pharmaceutical Research · 2013 · 126 citations

Pharmacy, Medicinal Chemistry, Pharmacology +14

l-Type Amino Acid Transporter 1 (LAT1/Lat1)-Utilizing Prodrugs Can Improve the Delivery of Drugs into Neurons, Astrocytes and Microglia

Johanna Huttunen, Soile Peltokangas, Mikko Gynther et al. · Scientific Reports · 2019 · 93 citations · Full text

Medicine, Neuroscience, Pharmacology +16

L-type amino acid transporter 1 utilizing prodrugs: How to achieve effective brain delivery and low systemic exposure of drugs

Elena Puris, Mikko Gynther, Johanna Huttunen et al. · Journal of Controlled Release · 2017 · 89 citations

Pharmacy, Neuroscience, Pharmacology +17

A Selective and Slowly Reversible Inhibitor of <scp>l</scp>-Type Amino Acid Transporter 1 (LAT1) Potentiates Antiproliferative Drug Efficacy in Cancer Cells

Kristiina M. Huttunen, Mikko Gynther, Johanna Huttunen et al. · Journal of Medicinal Chemistry · 2016 · 67 citations · Full text

Medicine, Oncology, Pharmacology +13

Quantitative Insight into the Design of Compounds Recognized by the <scp>L</scp>‐Type Amino Acid Transporter 1 (LAT1)

Henna Ylikangas, Kalle Malmioja, Lauri Peura et al. · ChemMedChem · 2014 · 66 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17