Elena Puris

L-type amino acid transporter 1 utilizing prodrugs: How to achieve effective brain delivery and low systemic exposure of drugs

Elena Puris, Mikko Gynther, Johanna Huttunen et al. · Journal of Controlled Release · 2017 · 84 citations

Utilizing Prodrugs, Neuropeptides, Medicine +10

A Selective and Slowly Reversible Inhibitor of <scp>l</scp>-Type Amino Acid Transporter 1 (LAT1) Potentiates Antiproliferative Drug Efficacy in Cancer Cells

Kristiina M. Huttunen, Mikko Gynther, Johanna Huttunen et al. · Journal of Medicinal Chemistry · 2016 · 66 citations · Full text

Chemoprevention Strategy, Lat1 Inhibitors, Pharmacotherapy +18

L-type amino acid transporter 1 utilizing prodrugs of ferulic acid revealed structural features supporting the design of prodrugs for brain delivery

Elena Puris, Mikko Gynther, Johanna Huttunen et al. · European Journal of Pharmaceutical Sciences · 2019 · 59 citations

Structural Features, Utilizing Prodrugs, Coiled-coil Drug Delivery +9

Alzheimer’s Disease Phenotype or Inflammatory Insult Does Not Alter Function of L-Type Amino Acid Transporter 1 in Mouse Blood-Brain Barrier and Primary Astrocytes

Mikko Gynther, Elena Puris, Soile Peltokangas et al. · Pharmaceutical Research · 2018 · 42 citations · Full text

Metabolomic, Lipidomic and Proteomic Characterisation of Lipopolysaccharide-induced Inflammation Mouse Model

Elena Puris, Štěpán Kouřil, Lukáš Najdekr et al. · Neuroscience · 2022 · 35 citations · Full text