Jessica P. Alexander

Conversion of Acetaminophen to the Bioactive N-Acylphenolamine AM404 via Fatty Acid Amide Hydrolase-dependent Arachidonic Acid Conjugation in the Nervous System

Edward D. Högestätt, Bo Jönsson, Anna Ermund et al. · Journal of Biological Chemistry · 2005 · 448 citations · Full text

Medicine, Neuroscience, Pharmacology +15

The serine hydrolase ABHD6 controls the accumulation and efficacy of 2-AG at cannabinoid receptors

William Marrs, Jacqueline L. Blankman, Eric A. Horne et al. · Nature Neuroscience · 2010 · 435 citations · Full text

Medicine, Biochemistry, Pharmacology +11

Mechanism of Carbamate Inactivation of FAAH: Implications for the Design of Covalent Inhibitors and In Vivo Functional Probes for Enzymes

Jessica P. Alexander, Benjamin F. Cravatt · Chemistry & Biology · 2005 · 225 citations · Full text

Life Sciences, Biochemistry, Pharmacology +16

Novel Mechanistic Class of Fatty Acid Amide Hydrolase Inhibitors with Remarkable Selectivity

Kyunghye Ahn, Douglas S. Johnson, Laura R. Fitzgerald et al. · Biochemistry · 2007 · 214 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +12

Identification of ABX-1431, a Selective Inhibitor of Monoacylglycerol Lipase and Clinical Candidate for Treatment of Neurological Disorders

Justin S. Cisar, Olivia D. Weber, Jason R. Clapper et al. · Journal of Medicinal Chemistry · 2018 · 153 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14