Thomas Friedberg

In vitro investigation of cytochrome P450-mediated metabolism of dietary flavonoids

Vibeke Breinholt, E.A Offord, C. Brouwer et al. · Food and Chemical Toxicology · 2002 · 161 citations

Dietary Flavonoids, Biochemistry, Medicine +4

An amperometric biosensor with human CYP3A4 as a novel drug screening tool

Shiba Joseph, James F. Rusling, Yuri Lvov et al. · Biochemical Pharmacology · 2003 · 160 citations

Drug Target, Engineering, Medicine +14

Endogenous drug transporters in in vitro and in vivo models for the prediction of drug disposition in man

Lay-Beng Goh, Kevin Spears, Denggao Yao et al. · Biochemical Pharmacology · 2002 · 156 citations

Vivo Models, Pharmacological Study, Pharmacodynamics +8

Stable expression of rat cytochrome P-450IIB1 cDNA in Chinese hamster cells (V79) and metabolic activation of aflatoxin B1.

Johannes Doehmer, Siddhant Dogra, Thomas Friedberg et al. · Proceedings of the National Academy of Sciences · 1988 · 152 citations · Full text

Genetics, Molecular Biology, Molecular Genetics +27

Characterization, localization and regulation of a novel phenobarbital-inducible form of cytochrome P₄₅₀, compared with three further P₄₅₀-isoenzymes, NADPH P₄₅₀-reductase, glutathione transferases and microsomal epoxide hydrolase

C. Roland Wolf, E. Moll, Thomas Friedberg et al. · Carcinogenesis · 1984 · 152 citations

Cytochrome P450 Reductase, Cytochromes P450, Experimental Pharmacology +18