Endogenous drug transporters in in vitro and in vivo models for the prediction of drug disposition in man

Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, homologues of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines.

Marcel Kool, Marcel de Haas, George L. Scheffer et al. · PubMed · 1997 · 898 citations

Medicine, Molecular Biology, Oncology +15

Pharmacological characterization of multidrug resistant MRP-transfected human tumor cells.

Susan P.C. Cole, Kathryn E. Sparks, Karen Fraser et al. · PubMed · 1994 · 774 citations

Medicine, Oncology, Pharmacology +15

Organic anion-transporting polypeptide B (OATP-B) and its functional comparison with three other OATPs of human liver

Gerd A. Kullak‐Ublick, Manfred G. Ismair, Bruno Stieger et al. · Gastroenterology · 2001 · 724 citations · Full text

Life Sciences, Biochemistry, Pharmacology +8

Drug Resistance and ATP-Dependent Conjugate Transport Mediated by the Apical Multidrug Resistance Protein, MRP2, Permanently Expressed in Human and Canine Cells

Yunhai Cui, Jörg König, Ulrike Buchholz et al. · Molecular Pharmacology · 1999 · 681 citations

Life Sciences, Biochemistry, Pharmacology +14

A novel human organic anion transporting polypeptide localized to the basolateral hepatocyte membrane

Jörg König, Yunhai Cui, Anne T. Nies et al. · American Journal of Physiology-Gastrointestinal and Liver Physiology · 2000 · 620 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13