Suining Lee

Targeting the Replication Checkpoint Using SCH 900776, a Potent and Functionally Selective CHK1 Inhibitor Identified via High Content Screening

Timothy J. Guzi, Kamil Paruch, Michael P. Dwyer et al. · Molecular Cancer Therapeutics · 2011 · 171 citations · Full text

Life Sciences, Molecular Biology, Oncology +17

Aurora Kinase Inhibitors Based on the Imidazo[1,2-<i>a</i>]pyrazine Core: Fluorine and Deuterium Incorporation Improve Oral Absorption and Exposure

Angela D. Kerekes, Sara Esposite, Ronald J. Doll et al. · Journal of Medicinal Chemistry · 2010 · 58 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Structure−Activity Relationship of 3-Substituted <i>N</i>-(Pyridinylacetyl)-4- (8-chloro-5,6-dihydro-11<i>H</i>-benzo[5,6]cyclohepta[1,2-<i>b</i>]pyridin-11-ylidene)- piperidine Inhibitors of Farnesyl-Protein Transferase:  Design and Synthesis of in Vivo Active Antitumor Compounds

F. George Njoroge, Bancha Vibulbhan, Dinananth F. Rane et al. · Journal of Medicinal Chemistry · 1997 · 53 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Effects of SCH 59228, an orally bioavailable farnesyl protein transferase inhibitor, on the growth of oncogene-transformed fibroblasts and a human colon carcinoma xenograft in nude mice

Ming Liu, Matthew Bryant, Jianping Chen et al. · Cancer Chemotherapy and Pharmacology · 1999 · 43 citations

Medicine, Oncology, Pharmacology +14

Discovery of a Potent, Injectable Inhibitor of Aurora Kinases Based on the Imidazo-[1,2-<i>a</i>]-Pyrazine Core

Tao Yu, Jayaram R. Tagat, Angela D. Kerekes et al. · ACS Medicinal Chemistry Letters · 2010 · 35 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17