Kosei Ishimaru

Doxorubicin causes ferroptosis and cardiotoxicity by intercalating into mitochondrial DNA and disrupting Alas1-dependent heme synthesis

Ko Abe, Masataka Ikeda, Tomomi Ide et al. · Science Signaling · 2022 · 136 citations · Full text

Life Sciences, Biochemistry, Cardiology +17

Iron Overload via Heme Degradation in the Endoplasmic Reticulum Triggers Ferroptosis in Myocardial Ischemia-Reperfusion Injury

Hiroko Deguchi Miyamoto, Masataka Ikeda, Tomomi Ide et al. · JACC Basic to Translational Science · 2022 · 134 citations · Full text

Life Sciences, Cardiology, Cell Biology +17

Excessive Hypoxia‐Inducible Factor‐1α Expression Induces Cardiac Rupture via p53‐Dependent Apoptosis After Myocardial Infarction

Masataka Ikeda, Tomomi Ide, Tomonori Tadokoro et al. · Journal of the American Heart Association · 2021 · 43 citations · Full text

Medicine, Cardiology, Molecular Medicine +14

Deferasirox Targeting Ferroptosis Synergistically Ameliorates Myocardial Ischemia Reperfusion Injury in Conjunction With Cyclosporine A

Kosei Ishimaru, Masataka Ikeda, Hiroko Deguchi Miyamoto et al. · Journal of the American Heart Association · 2023 · 40 citations · Full text

Life Sciences, Cell Biology, Pharmacology +15

Ethoxyquin is a Competent Radical-Trapping Antioxidant for Preventing Ferroptosis in Doxorubicin Cardiotoxicity

Tomonori Tadokoro, Masataka Ikeda, Ko Abe et al. · Journal of Cardiovascular Pharmacology · 2022 · 28 citations

Medicine, Cardiology, Pharmacology +17