William J. Fredericks

Fusion of a fork head domain gene to PAX3 in the solid tumour alveolar rhabdomyosarcoma

Naomi Galili, Richard J. Davis, William J. Fredericks et al. · Nature Genetics · 1993 · 899 citations

Tumor Biology, Tumor Heterogeneity, Medicine +8

KAP-1, a novel corepressor for the highly conserved KRAB repression domain.

Joshua R. Friedman, William J. Fredericks, D. E. Jensen et al. · Genes & Development · 1996 · 664 citations · Full text

Novel Corepressor, Molecular Regulation, Molecular Biology +18

PHD Domain-Mediated E3 Ligase Activity Directs Intramolecular Sumoylation of an Adjacent Bromodomain Required for Gene Silencing

Alexey V. Ivanov, Hongzhuang Peng, Vyacheslav Yurchenko et al. · Molecular Cell · 2007 · 414 citations · Full text

Transcriptional Regulation, Molecular Regulation, Medicine +8

KAP-1 Corepressor Protein Interacts and Colocalizes with Heterochromatic and Euchromatic HP1 Proteins: a Potential Role for Krüppel-Associated Box–Zinc Finger Proteins in Heterochromatin-Mediated Gene Silencing

Robert F. Ryan, D. Schultz, Kasirajan Ayyanathan et al. · Molecular and Cellular Biology · 1999 · 382 citations · Full text

Molecular Regulation, Genetics, Molecular Biology +21

The PAX3-FKHR Fusion Protein Created by the t(2;13) Translocation in Alveolar Rhabdomyosarcomas Is A More Potent Transcriptional Activator than PAX3

William J. Fredericks, Naomi Galili, Sunil Mukhopadhyay et al. · Molecular and Cellular Biology · 1995 · 304 citations · Full text

Tumor Biology, Transcriptional Regulation, Potent Transcriptional Activator +13