PHD Domain-Mediated E3 Ligase Activity Directs Intramolecular Sumoylation of an Adjacent Bromodomain Required for Gene Silencing

SETDB1: a novel KAP-1-associated histone H3, lysine 9-specific methyltransferase that contributes to HP1-mediated silencing of euchromatic genes by KRAB zinc-finger proteins

D. Schultz, Kasirajan Ayyanathan, Dmitri Negorev et al. · Genes & Development · 2002 · 1.3K citations · Full text

A PHD finger of NURF couples histone H3 lysine 4 trimethylation with chromatin remodelling

Joanna Wysocka, Tomek Swigut, Hua Xiao et al. · Nature · 2006 · 1.2K citations

Histone Modifications, Chromatin, Chromatin Structure +12

ING2 PHD domain links histone H3 lysine 4 methylation to active gene repression

Xiaobing Shi, Tao Hong, Kay L. Walter et al. · Nature · 2006 · 920 citations · Full text

Histone Modifications, Chromatin, Transcriptional Regulation +15

Molecular basis for site-specific read-out of histone H3K4me3 by the BPTF PHD finger of NURF

Haitao Li, Serge Ilin, Wooikoon Wang et al. · Nature · 2006 · 798 citations · Full text

Histone Modifications, Epigenetic Change, Molecular Biology +16

KAP-1, a novel corepressor for the highly conserved KRAB repression domain.

Joshua R. Friedman, William J. Fredericks, D. E. Jensen et al. · Genes & Development · 1996 · 664 citations · Full text

Novel Corepressor, Molecular Regulation, Molecular Biology +18