Marcelo Simon Sola

Antigen-selective modulation of AAV immunogenicity with tolerogenic rapamycin nanoparticles enables successful vector re-administration

Amine Meliani, Florence Boisgérault, Romain Hardet et al. · Nature Communications · 2018 · 254 citations · Full text

Pharmacy, Biotechnology, Immunology +17

Influence of Pre-existing Anti-capsid Neutralizing and Binding Antibodies on AAV Vector Transduction

Zachary Fitzpatrick, Christian Leborgne, Elena Barbon et al. · Molecular Therapy — Methods & Clinical Development · 2018 · 197 citations · Full text

Life Sciences, Immunology, Molecular Biology +13

Enhanced liver gene transfer and evasion of preexisting humoral immunity with exosome-enveloped AAV vectors

Amine Meliani, Florence Boisgérault, Zachary Fitzpatrick et al. · Blood Advances · 2017 · 123 citations · Full text

Life Sciences, Immunology, Molecular Biology +16

AAV Gene Transfer with Tandem Promoter Design Prevents Anti-transgene Immunity and Provides Persistent Efficacy in Neonate Pompe Mice

Pasqualina Colella, Pauline Sellier, Helena Costa Verdera et al. · Molecular Therapy — Methods & Clinical Development · 2018 · 73 citations · Full text

Pharmacy, Genetics, Molecular Genetics +16

A translationally optimized AAV-UGT1A1 vector drives safe and long-lasting correction of Crigler-Najjar syndrome

Giuseppe Ronzitti, Giulia Bortolussi, Remco van Dijk et al. · Molecular Therapy — Methods & Clinical Development · 2016 · 62 citations · Full text

Life Sciences, Biotechnology, Molecular Biology +16