Differential Effects of Physiologically Relevant Hypoxic Conditions on T Lymphocyte Development and Effector Functions

Charles C. Caldwell, Hidefumi Kojima, Dmitriy Lukashev, +4

The Journal of Immunology

Lymphocyte DevelopmentT-regulatory CellImmunologyImmune RegulationImmunologic Mechanism +20

Two distinct pathways of specific killing revealed by perforin mutant cytotoxic T lymphocytes

Hidefumi Kojima, Nobukata Shinohara, Satoko Hanaoka, +12

Immunity

Autoimmune DiseasePathogenesisAutophagyImmunologyApoptosis +10

Herpes Simplex Virus as an in Situ Cancer Vaccine for the Induction of Specific Anti-Tumor Immunity

Masahiro Toda, Samuel D. Rabkin, Hidefumi Kojima, +1

Human Gene Therapy

ImmunologyImmunoeditingPathologyImmunotherapyTumor Biology +24

Notch2 integrates signaling by the transcription factors RBP-J and CREB1 to promote T cell cytotoxicity

Yoichi Maekawa, Yoshiaki Minato, Chieko Ishifune, +9

Nature Immunology

Transcriptional RegulationSignal TransductionSignaling PathwayCell RegulationImmunology +7

Abnormal B lymphocyte development and autoimmunity in hypoxia-inducible factor 1α-deficient chimeric mice

Hidefumi Kojima, Hua Gu, Saeko Nomura, +5

Proceedings of the National Academy of Sciences

Cutting Edge: Hypoxia-Inducible Factor 1α and Its Activation-Inducible Short Isoform I.1 Negatively Regulate Functions of CD4+ and CD8+ T Lymphocytes

Dmitriy Lukashev, Boris Klebanov, Hidefumi Kojima, +6

The Journal of Immunology

Memory of Extracellular Adenosine A2A Purinergic Receptor-mediated Signaling in Murine T Cells

M. Koshiba, Hidefumi Kojima, Steve Huang, +2

Journal of Biological Chemistry

In Situ Cancer Vaccination: An IL-12 Defective Vector/Replication-Competent Herpes Simplex Virus Combination Induces Local and Systemic Antitumor Activity

Masahiro Toda, Robert L. Martuza, Hidefumi Kojima, +1

The Journal of Immunology

Viral ReplicationImmunologyImmunoeditingPathologyImmunotherapy +17

BAFF/BLyS can potentiate B-cell selection with the B-cell coreceptor complex

Hidenori Hase, Yumiko Kanno, Masaru Kojima, +9

Blood

TACI regulates IgA production by APRIL in collaboration with HSPG

Daisuke Sakurai, Hidenori Hase, Yumiko Kanno, +3

Blood