Prevotellaceae produces butyrate to alleviate PD-1/PD-L1 inhibitor-related cardiotoxicity via PPARα-CYP4X1 axis in colonic macrophages

Yaxin Chen, Yanzhuo Liu, Yang Wang, +7

Journal of Experimental & Clinical Cancer Research

Inhibition of COX-2, mPGES-1 and CYP4A by isoliquiritigenin blocks the angiogenic Akt signaling in glioma through ceRNA effect of miR-194-5p and lncRNA NEAT1

Chenlong Wang, Yaxin Chen, Yang Wang, +7

Journal of Experimental & Clinical Cancer Research

Modulation of intestinal microbiota by glycyrrhizic acid prevents high-fat diet-enhanced pre-metastatic niche formation and metastasis

Miao Qiu, Keqing Huang, Yanzhuo Liu, +8

Mucosal Immunology

DysbiosisMicrobiotaImmunologyGut MicrobiologyMicrobiology +5

Increased expression of CYP4Z1 promotes tumor angiogenesis and growth in human breast cancer

Wei Yu, Hongyan Chai, Ying Li, +9

Toxicology and Applied Pharmacology

Cancer ResearchBreast OncologyMedicineCancer GrowthHuman Breast Cancer +9

Glabridin Prevents Doxorubicin-Induced Cardiotoxicity Through Gut Microbiota Modulation and Colonic Macrophage Polarization in Mice

Keqing Huang, Yanzhuo Liu, Honglin Tang, +6

Frontiers in Pharmacology

Inhibition of COX-2/mPGES-1 and 5-LOX in macrophages by leonurine ameliorates monosodium urate crystal-induced inflammation

Yanzhuo Liu, Chenfan Duan, Honglei Chen, +7

Toxicology and Applied Pharmacology

InflammationAnti-inflammatoryBiochemistryMedicineImmunology +9

Frontline Science: Reprogramming COX-2, 5-LOX, and CYP4A-mediated arachidonic acid metabolism in macrophages by salidroside alleviates gouty arthritis

Yanzhuo Liu, Honglin Tang, Xiaoxiao Liu, +7

Journal of Leukocyte Biology

Lipid PeroxidationImmunologyRenal InflammationFrontline ScienceCox-2 Inhibitor Celecoxib +17

Dopamine induces growth inhibition and vascular normalization through reprogramming M2-polarized macrophages in rat C6 glioma

Tian Qin, Chenlong Wang, Xuewei Chen, +9

Toxicology and Applied Pharmacology

Neuro-oncologyVascular NormalizationMedicineGrowth InhibitionBrain-immune Interaction +9

High flow nasal cannula oxygen therapy versus non-invasive ventilation for acute exacerbations of chronic obstructive pulmonary disease with acute-moderate hypercapnic respiratory failure: a randomized controlled non-inferiority trial

Dingyu Tan, Bingxia Wang, Peng Cao, +6

Critical Care

Inhibition of COX-2 and EGFR by Melafolone Improves Anti-PD-1 Therapy through Vascular Normalization and PD-L1 Downregulation in Lung Cancer

Honglin Tang, Yanzhuo Liu, Chenlong Wang, +8

Journal of Pharmacology and Experimental Therapeutics