Hongyan Chai

Isoliquiritigenin, a flavonoid from licorice, blocks M2 macrophage polarization in colitis-associated tumorigenesis through downregulating PGE2 and IL-6

Haixia Zhao, Xinhua Zhang, Xuewei Chen et al. · Toxicology and Applied Pharmacology · 2014 · 97 citations

Inflammation, Cytokine, Anti-inflammatory +9

Isoliquiritigenin induces growth inhibition and apoptosis through downregulating arachidonic acid metabolic network and the deactivation of PI3K/Akt in human breast cancer

Ying Li, Haixia Zhao, Yuzhong Wang et al. · Toxicology and Applied Pharmacology · 2013 · 91 citations

Medicine, Apoptosis, Cell Death +8

Increased expression of CYP4Z1 promotes tumor angiogenesis and growth in human breast cancer

Wei Yu, Hongyan Chai, Ying Li et al. · Toxicology and Applied Pharmacology · 2012 · 85 citations · Full text

Cancer Research, Breast Oncology, Medicine +11

Tectoridin, an isoflavone glycoside from the flower of Pueraria lobata, prevents acute ethanol-induced liver steatosis in mice

Yu Xiong, Yuqing Yang, Jin Yang et al. · Toxicology · 2010 · 84 citations

Pueraria Lobata, Hepatology, Medicine +11

Downregulation of COX-2 and CYP 4A signaling by isoliquiritigenin inhibits human breast cancer metastasis through preventing anoikis resistance, migration and invasion

Hao Zheng, Ying Li, Yuzhong Wang et al. · Toxicology and Applied Pharmacology · 2014 · 68 citations

Cyp 4A, Anoikis Resistance, Signaling Pathway +8