Regulation of the hedgehog signaling by the mitogen‐activated protein kinase cascade in gastric cancer

Motoko Seto, Miki Ohta, Yoshinari Asaoka, +10

Molecular Carcinogenesis

Down-Regulation of Hedgehog-Interacting Protein through Genetic and Epigenetic Alterations in Human Hepatocellular Carcinoma

Motohisa Tada, Fumihiko Kanai, Yasuo Tanaka, +10

Clinical Cancer Research

Decreased Expression of the RAS-GTPase Activating Protein RASAL1 Is Associated With Colorectal Tumor Progression

Miki Ohta, Motoko Seto, Hideaki Ijichi, +10

Gastroenterology

Cancer ResearchMedicinePathologyColorectal CancerColorectal Tumor Progression +5

Different subtypes of intraductal papillary mucinous neoplasm in the pancreas have distinct pathways to pancreatic cancer progression

Dai Mohri, Yoshinari Asaoka, Hideaki Ijichi, +15

Journal of Gastroenterology

Pancreatic CancerPancreatic Fluid CollectionMedicineSurgical PathologyPathology +6

Gastric cancer cell line Hs746T harbors a splice site mutation of c-Met causing juxtamembrane domain deletion

Yoshinari Asaoka, Motohisa Tada, Tsuneo Ikenoue, +14

Biochemical and Biophysical Research Communications

Tumor BiologyJuxtamembrane Domain DeletionGastrointestinal OncologySplice Site MutationMedicine +6

Gain of GRHL2 is associated with early recurrence of hepatocellular carcinoma

Yasuo Tanaka, Fumihiko Kanai, Motohisa Tada, +12

Journal of Hepatology

Early RecurrenceHepatologyMedicinePathologyLiver Cancer +5

Dysregulated Expression of Stem Cell Factor Bmi1 in Precancerous Lesions of the Gastrointestinal Tract

Keisuke Tateishi, Miki Ohta, Fumihiko Kanai, +13

Clinical Cancer Research

Altered composition of fatty acids exacerbates hepatotumorigenesis during activation of the phosphatidylinositol 3-kinase pathway

Yotaro Kudo, Yasuo Tanaka, Keisuke Tateishi, +20

Journal of Hepatology

Signal TransductionLipid SynthesisBiochemistryFatty AcidsPhosphatidylinositol 3-Kinase Pathway +13

Vonoprazan <i>versus</i> conventional proton pump inhibitor‐based triple therapy as first‐line treatment against <i>Helicobacter pylori</i> : A multicenter retrospective study in clinical practice

Satoki Shichijo, Yoshihiro Hirata, Ryota Niikura, +18

Journal of Digestive Diseases

Identification of a Suppressive Mechanism for Hedgehog Signaling through a Novel Interaction of Gli with 14-3-3

Yoshinari Asaoka, Fumihiko Kanai, Tohru Ichimura, +11

Journal of Biological Chemistry

Signal TransductionDevelopmental BiologyHedgehog SignalingSuppressive MechanismSignaling Pathway +5