Down-Regulation of Hedgehog-Interacting Protein through Genetic and Epigenetic Alterations in Human Hepatocellular Carcinoma - Concepedia

Concepedia

Publication | Open Access

Down-Regulation of Hedgehog-Interacting Protein through Genetic and Epigenetic Alterations in Human Hepatocellular Carcinoma

DOI Full Paper Access

96

Citations

44

References

2008

Year

Motohisa Tada, Fumihiko Kanai, Yasuo Tanaka, Keisuke Tateishi, Miki Ohta, Yoshinari Asaoka, Motoko Seto, Ryosuke Muroyama, Kenichi Fukai, Fumio Imazeki,

Clinical Cancer Research

Abstract

The down-regulation of HHIP transcription is due to DNA hypermethylation and/or LOH, and Hh signal activation through the inactivation of HHIP may be implicated in the pathogenesis of human HCC.

References

	Year	Citations

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