Detection of ras gene mutations in pancreatic juice and peripheral blood of patients with pancreatic adenocarcinoma.

Motohisa Tada, Masao Omata, S Kawai, +4

PubMed

Ras Gene MutationsTumor BiologyMutant Ras GenesPancreatic CancerMedicine +11

Inhibiting Cxcr2 disrupts tumor-stromal interactions and improves survival in a mouse model of pancreatic ductal adenocarcinoma

Hideaki Ijichi, Anna Chytil, Agnieszka E. Gorska, +13

Journal of Clinical Investigation

Regulation of the hedgehog signaling by the mitogen‐activated protein kinase cascade in gastric cancer

Motoko Seto, Miki Ohta, Yoshinari Asaoka, +10

Molecular Carcinogenesis

3‐Deazaneplanocin A is a promising therapeutic agent for the eradication of tumor‐initiating hepatocellular carcinoma cells

Tetsuhiro Chiba, Eiichiro Suzuki, Masamitsu Negishi, +9

International Journal of Cancer

Apoptosis signal-regulating kinase 1 and cyclin D1 compose a positive feedback loop contributing to tumor growth in gastric cancer

Yoku Hayakawa, Yoshihiro Hirata, Hayato Nakagawa, +14

Proceedings of the National Academy of Sciences

Cell Growth Inhibition and Gene Expression Induced by the Histone Deacetylase Inhibitor, Trichostatin A, on Human Hepatoma Cells

Tetsuhiro Chiba, Osamu Yokosuka, Kenichi Fukai, +5

Oncology

Down-Regulation of Hedgehog-Interacting Protein through Genetic and Epigenetic Alterations in Human Hepatocellular Carcinoma

Motohisa Tada, Fumihiko Kanai, Yasuo Tanaka, +10

Clinical Cancer Research

Identification of genes up-regulated by histone deacetylase inhibition with cDNA microarray and exploration of epigenetic alterations on hepatoma cells

Tetsuhiro Chiba, Osamu Yokosuka, Makoto Arai, +6

Journal of Hepatology

Histone ModificationsChromatinFunctional GenomicsChromatin RemodelingEpigenetic Alterations +10

Decreased Expression of the RAS-GTPase Activating Protein RASAL1 Is Associated With Colorectal Tumor Progression

Miki Ohta, Motoko Seto, Hideaki Ijichi, +10

Gastroenterology

Cancer ResearchMedicinePathologyColorectal CancerColorectal Tumor Progression +5

Different subtypes of intraductal papillary mucinous neoplasm in the pancreas have distinct pathways to pancreatic cancer progression

Dai Mohri, Yoshinari Asaoka, Hideaki Ijichi, +15

Journal of Gastroenterology

Pancreatic CancerPancreatic Fluid CollectionMedicineSurgical PathologyPathology +6