Gut microbiome pattern reflects healthy ageing and predicts survival in humans

Tomasz Wilmanski, Christian Diener, Noa Rappaport, +18

Nature Metabolism

ProbioticDysbiosisLongevityGlobal HealthMicrobiota +9

Sensitivity and Selectivity in Protein Similarity Searches: A Comparison of Smith–Waterman in Hardware to BLAST and FASTA

Eugene G. Shpaer, Max Robinson, David P. Yee, +3

Genomics

Protein Similarity SearchesEngineeringStructural BioinformaticsNatural SciencesSequence Analysis +8

A New Method for Straightening DNA Molecules for Optical Restriction Mapping

Hiroki Yokota, Frank Johnson, Hailing Lu, +6

Nucleic Acids Research

Optimal Scaling of Digital Transcriptomes

Gustavo Glusman, Juan Caballero-Pérez, Max Robinson, +2

PLoS ONE

GeneticsMolecular BiologyTranscriptomics TechnologyGenomicsSequence Alignment +18

Integrative proteomics identifies a conserved Aβ amyloid responsome, novel plaque proteins, and pathology modifiers in Alzheimer’s disease

Yona Levites, Eric B. Dammer, Yong Ran, +32

Cell Reports Medicine

Amyloid βProteasomeSynaptic SignalingProteomic TechnologyAlzheimer's Disease +19

Microglia show differential transcriptomic response to Aβ peptide aggregates ex vivo and in vivo

Karen N. McFarland, Awilda M. Rosario, Thomas B. Ladd, +11

Life Science Alliance

The geometry of clinical labs and wellness states from deeply phenotyped humans

Anat Zimmer, Yael Korem, Noa Rappaport, +9

Nature Communications

Systematic measurement of transcription factor-DNA interactions by targeted mass spectrometry identifies candidate gene regulatory proteins

Hamid Mirzaei, Theo Knijnenburg, Bong Keun Kim, +11

Proceedings of the National Academy of Sciences

GeneticsBiological Mass SpectrometryMolecular BiologyTranscriptomics TechnologyGene Regulatory Proteins +23

Index-ion Triggered MS2 Ion Quantification: A Novel Proteomics Approach for Reproducible Detection and Quantification of Targeted Proteins in Complex Mixtures

Wei Yan, Jie Luo, Max Robinson, +3

Molecular & Cellular Proteomics

Ms2 Ion QuantificationAccurate Peptide QuantificationComplex MixturesBiological Mass SpectrometryMolecular Biology +18

Sex, obesity, diabetes, and exposure to particulate matter among patients with severe asthma: Scientific insights from a comparative analysis of open clinical data sources during a five-day hackathon

Karamarie Fecho, Stanley C. Ahalt, Saravanan Arunachalam, +15

Journal of Biomedical Informatics

AsthmaEpidemiologyFive-day HackathonRespiratory ToxicologyEnvironmental Health +9