Microglial NFκB-TNFα hyperactivation induces obsessive–compulsive behavior in mouse models of progranulin-deficient frontotemporal dementia

Grietje Krabbe, Sakura Minami, Jon Iker Etchegaray, +19

Proceedings of the National Academy of Sciences

Microglial microRNAs mediate sex-specific responses to tau pathology

Lay Kodama, Elmer Guzman, Jon Iker Etchegaray, +13

Nature Neuroscience

MedicineImmunologyDegenerative PathologyBrain-immune InteractionNeuroimmunology +2

Interpreting an apoptotic corpse as anti-inflammatory involves a chloride sensing pathway

Justin S. A. Perry, Sho Morioka, Christopher B. Medina, +7

Nature Cell Biology

InflammationAnti-inflammatoryAutoimmune DiseaseAllergyApoptotic Corpse +8

Draper acts through the JNK pathway to control synchronous engulfment of dying germline cells by follicular epithelial cells

Jon Iker Etchegaray, Allison K. Timmons, Adam P. Klein, +5

Development

Cell DeathCell ProliferationCytoskeletonCellular PhysiologyEfficient Removal +16

Metabolic adaptation supports enhanced macrophage efferocytosis in limited-oxygen environments

Yating Wang, Alissa Trzeciak, Waleska Saitz Rojas, +8

Cell Metabolism

Metabolic Adaptation SupportsPhysiologyAutophagyMetabolic RegulationMetabolic Remodeling +4

Phagocytosis genes nonautonomously promote developmental cell death in the <i>Drosophila</i> ovary

Allison K. Timmons, Albert A. Mondragon, Claire E. Schenkel, +6

Proceedings of the National Academy of Sciences

ApoptosisCell DeathPhagocytosis GenesCell Death MechanismsCellular Physiology +18

Defective Phagocytic Corpse Processing Results in Neurodegeneration and Can Be Rescued by TORC1 Activation

Jon Iker Etchegaray, Emma J. Elguero, Jennifer Tran, +3

Journal of Neuroscience

Pannexin 1 drives efficient epithelial repair after tissue injury

Christopher D. Lucas, Christopher B. Medina, Finnius A. Bruton, +13

Science Immunology

Rapid unleashing of macrophage efferocytic capacity via transcriptional pause release

Turan Tufan, Gamze Cömertpay, Ambra Villani, +18

Nature

Transcriptional RegulationImmunologyRapid UnleashingEndocytic PathwayGene Expression +4

Phagocytosis in the retina promotes local insulin production in the eye

Jon Iker Etchegaray, Shannon Kelley, Kristen K. Penberthy, +19

Nature Metabolism

Diabetic RetinopathyOcular DiseaseSignal TransductionLocal Insulin ProductionOphthalmology +7