Longitudinal Isolation of Potent Near-Germline SARS-CoV-2-Neutralizing Antibodies from COVID-19 Patients

Christoph Kreer, Matthias Zehner, Timm Weber, +25

Cell

Kinetics and correlates of the neutralizing antibody response to SARS-CoV-2 infection in humans

Kanika Vanshylla, Veronica Di Cristanziano, Franziska Kleipass, +23

Cell Host & Microbe

VaccinationSars-cov-2 InfectionVaccine TargetHumoral ResponseImmunology +6

The Translocon Protein Sec61 Mediates Antigen Transport from Endosomes in the Cytosol for Cross-Presentation to CD8+ T Cells

Matthias Zehner, Andrea L. J. Marschall, Erik Bos, +9

Immunity

Signal TransductionNatural SciencesCell TraffickingImmunologyEndocytic Pathway +10

Long‐lived macrophage reprogramming drives spike protein‐mediated inflammasome activation in COVID‐19

Sebastian J. Theobald, Alexander Simonis, Theodoros Georgomanolis, +30

EMBO Molecular Medicine

Inflammasome ActivationInnate Immune SystemViral PathogenesisImmunologyImmune Regulation +19

Polyclonal and convergent antibody response to Ebola virus vaccine rVSV-ZEBOV

Stefanie Ehrhardt, Matthias Zehner, Verena Krähling, +15

Nature Medicine

VaccinationVaccine DevelopmentImmunologyVirologyConvergent Antibody Response +4

SARS-CoV-2 Omicron sublineages exhibit distinct antibody escape patterns

Henning Gruell, Kanika Vanshylla, Michael Korenkov, +10

Cell Host & Microbe

ImmunologyVirologySars-cov-2 Omicron SublineagesAntibody EngineeringMedicine +1

Mannose receptor polyubiquitination regulates endosomal recruitment of p97 and cytosolic antigen translocation for cross-presentation

Matthias Zehner, Achmet Imam Chasan, Verena Schuette, +4

Proceedings of the National Academy of Sciences

HistocompatibilityMr PolyubiquitinationEndosomal RecruitmentAntigen TranslocationImmunology +18

Intranasal Administration of a Monoclonal Neutralizing Antibody Protects Mice against SARS-CoV-2 Infection

Sandro Halwe, Alexandra Kupke, Kanika Vanshylla, +25

Viruses

Viral PathogenesisImmunologyMonoclonal Neutralizing AntibodiesAntiviral DrugViral Structural Protein +14

Longitudinal isolation of potent near-germline SARS-CoV-2-neutralizing antibodies from COVID-19 patients

Christoph Kreer, Matthias Zehner, Timm Weber, +24

Viral DiagnosticsHumoral ResponseImmunologyImmunodominanceSars-cov-2 Neutralizing Antibodies +17

Structural Basis for a Convergent Immune Response against Ebola Virus

Hadas Cohen‐Dvashi, Matthias Zehner, Stefanie Ehrhardt, +4

Cell Host & Microbe

VaccinationHost ResponseVaccine TargetImmunologyAntiviral Response +4