Lawrence R. Gray

Hepatic Mitochondrial Pyruvate Carrier 1 Is Required for Efficient Regulation of Gluconeogenesis and Whole-Body Glucose Homeostasis

Lawrence R. Gray, Rasheda Sultana, Adam J. Rauckhorst et al. · Cell Metabolism · 2015 · 226 citations · Full text

Metabolic Syndrome, Energy Metabolism, Mitochondrial Function +12

Mitochondrial pyruvate carriers are required for myocardial stress adaptation

Yuan Zhang, Paul Taufalele, Jesse D. Cochran et al. · Nature Metabolism · 2020 · 139 citations · Full text

Mitochondrial Biogenesis, Biochemistry, Mitochondrial Function +6

The mitochondrial pyruvate carrier mediates high fat diet-induced increases in hepatic TCA cycle capacity

Adam J. Rauckhorst, Lawrence R. Gray, Ryan D. Sheldon et al. · Molecular Metabolism · 2017 · 82 citations · Full text

Disrupting Mitochondrial Pyruvate Uptake Directs Glutamine into the TCA Cycle away from Glutathione Synthesis and Impairs Hepatocellular Tumorigenesis

Sean C. Tompkins, Ryan D. Sheldon, Adam J. Rauckhorst et al. · Cell Reports · 2019 · 81 citations · Full text

Impaired skeletal muscle mitochondrial pyruvate uptake rewires glucose metabolism to drive whole-body leanness

Arpit Sharma, Lalita Oonthonpan, Ryan D. Sheldon et al. · eLife · 2019 · 68 citations · Full text

Obesity, Metabolic Syndrome, Skeletal Muscle Mpc +15