Aaron N. Hata

<i>EGFR</i> Mutations and <i>ALK</i> Rearrangements Are Associated with Low Response Rates to PD-1 Pathway Blockade in Non–Small Cell Lung Cancer: A Retrospective Analysis

Justin F. Gainor, Alice T. Shaw, Lecia V. Sequist et al. · Clinical Cancer Research · 2016 · 1.2K citations · Full text

Tumor cells can follow distinct evolutionary paths to become resistant to epidermal growth factor receptor inhibition

Aaron N. Hata, Matthew J. Niederst, Hannah L. Archibald et al. · Nature Medicine · 2016 · 968 citations · Full text

Tumor Biology, Developmental Biology, Distinct Evolutionary Paths +7

A single-cell and single-nucleus RNA-Seq toolbox for fresh and frozen human tumors

Michal Slyper, Caroline Porter, Orr Ashenberg et al. · Nature Medicine · 2020 · 751 citations · Full text

Clinical Acquired Resistance to KRASG12C Inhibition through a Novel KRAS Switch-II Pocket Mutation and Polyclonal Alterations Converging on RAS–MAPK Reactivation

Noritaka Tanaka, Chendi Li, Meagan B. Ryan et al. · Cancer Discovery · 2021 · 475 citations · Full text

Cycling cancer persister cells arise from lineages with distinct programs

Yaara Oren, Michael Tsabar, Michael S. Cuoco et al. · Nature · 2021 · 472 citations · Full text

Tumor Biology, Lineage Plasticity, Cell Division +8