J. Kelder

Polar Molecular Surface as a Dominating Determinant for Oral Absorption and Brain Penetration of Drugs

J. Kelder, Peter D. J. Grootenhuis, Denis M. Bayada et al. · Pharmaceutical Research · 1999 · 792 citations

Steroid and G Protein Binding Characteristics of the Seatrout and Human Progestin Membrane Receptor α Subtypes and Their Evolutionary Origins

Peter Thomas, Yefei Pang, Jing Dong et al. · Endocrinology · 2006 · 302 citations · Full text

Immunology, Gynecology, Reproductive Biology +22

Use of physicochemical calculation of pKa and CLogP to predict phospholipidosis-inducing potential

Jan-Peter H. T. M. Ploemen, J. Kelder, Theo Hafmans et al. · Experimental and Toxicologic Pathology · 2004 · 145 citations

Proteinlipid Interaction, Biochemistry, Medicine +11

A signaling-selective, nanomolar potent allosteric low molecular weight agonist for the human luteinizing hormone receptor

Chris J. van Koppen, Guido J.R. Zaman, C. Marco Timmers et al. · Naunyn-Schmiedeberg s Archives of Pharmacology · 2008 · 97 citations

Molecular Pharmacology, Molecular Physiology, Signal Transduction +9

Comparison between steroid binding to membrane progesterone receptor α (mPRα) and to nuclear progesterone receptor: Correlation with physicochemical properties assessed by comparative molecular field analysis and identification of mPRα-specific agonists

J. Kelder, Rita Azevedo, Yefei Pang et al. · Steroids · 2010 · 91 citations

Molecular Pharmacology, Endocrine Mechanism, Medicine +8