Integrated Transcript and Genome Analyses Reveal NKX2-1 and MEF2C as Potential Oncogenes in T Cell Acute Lymphoblastic Leukemia

Irene Homminga, Rob Pieters, Anton W. Langerak, +21

Cancer Cell

Hematological MalignancyMixed-phenotype Acute LeukemiaImmunologyPotential OncogenesAdult T-cell Leukemia-lymphoma +2

Disruption of the BCL11B gene through inv(14)(q11.2q32.31) results in the expression of BCL11B-TRDC fusion transcripts and is associated with the absence of wild-type BCL11B transcripts in T-ALL

Grzegorz K. Przybylski, W. A. Dik, Jens Wanzeck, +10

Leukemia

Wild-type Bcl11b TranscriptsImmunogeneticsBcl11b GeneImmunologyBcl11b-trdc Fusion Transcripts +4

BIOMED-2 Multiplex Immunoglobulin/T-Cell Receptor Polymerase Chain Reaction Protocols Can Reliably Replace Southern Blot Analysis in Routine Clonality Diagnostics

Yorick Sandberg, Ellen J. van Gastel-Mol, Brenda Verhaaf, +3

Journal of Molecular Diagnostics

Immunocytochemical TechniqueAutoimmune DiseaseLaboratory ImmunologyMedicineImmunodeficiencies +7

The predictive value of lipoprotein lipase for survival in chronic lymphocytic leukemia.

Mars B. vanʼt Veer, Anne M Brooijmans, Anton W. Langerak, +5

PubMed

Identification and Characterization of the Interaction between Tuberin and 14-3-3ζ

Mark Nellist, Miriam Goedbloed, Christa de Winter, +6

Journal of Biological Chemistry

Protein FunctionSignal Transduction14-3-3Zeta BindingBiochemistryNatural Sciences +9

Different chromosomal breakpoints impact the level of LMO2 expression in T-ALL

Willem A. Dik, Bertrand Nadel, Grzegorz K. Przybylski, +8

Blood

Human T-cell lines with well-defined T-cell receptor gene rearrangements as controls for the BIOMED-2 multiplex polymerase chain reaction tubes

Yorick Sandberg, Brenda Verhaaf, Ellen J. van Gastel-Mol, +7

Leukemia

Cell TherapyT-regulatory CellImmunologyHuman T-cell LinesCell Biology +4

Unraveling the Consecutive Recombination Events in the Human <i>IGK</i> Locus

Anton W. Langerak, Bertrand Nadel, Anneke de Torbal, +5

The Journal of Immunology

T-cell receptor Vβ CDR3 oligoclonality frequently occurs in childhood refractory cytopenia (MDS-RC) and severe aplastic anemia

Andrica C. H. de Vries, Anton W. Langerak, Brenda Verhaaf, +8

Leukemia

Bone Marrow FailureAutoimmune DiseaseChildhood Refractory CytopeniaImmunodeficienciesImmunology +9

PCR-Based Analysis of Rearranged Immunoglobulin or T-Cell Receptor Genes by GeneScan Analysis or Heteroduplex Analysis for Clonality Assessment in Lymphoma Diagnostics

Elke Boone, Brenda Verhaaf, Anton W. Langerak

Methods in molecular biology