Akihiro Mizutani

KN-62, 1-[N,O-bis(5-isoquinolinesulfonyl)-N-methyl-L-tyrosyl]-4-phenylpiperazi ne, a specific inhibitor of Ca2+/calmodulin-dependent protein kinase II.

Hiroshi Tokumitsu, Takashi Chijiwa, Masatoshi Hagiwara et al. · Journal of Biological Chemistry · 1990 · 625 citations · Full text

Specific Inhibitor, Molecular Biology, Pharmacotherapy +23

An important role of heparan sulfate proteoglycan (perlecan) in a model system for the deposition and persistence of fibrillar aβ-amyloid in rat brain

Alan D. Snow, Raymond Sekiguchi, David Nochlin et al. · Neuron · 1994 · 298 citations

Neurodegenerative Diseases, Biochemistry, Degenerative Pathology +8

Regulation of TRPC6 Channel Activity by Tyrosine Phosphorylation

Chihiro Hisatsune, Yukiko Kuroda, Kyoko Nakamura et al. · Journal of Biological Chemistry · 2004 · 197 citations · Full text

IRBIT, a Novel Inositol 1,4,5-Trisphosphate (IP3) Receptor-binding Protein, Is Released from the IP3 Receptor upon IP3 Binding to the Receptor

Hideaki Ando, Akihiro Mizutani, Toru Matsuura et al. · Journal of Biological Chemistry · 2003 · 195 citations · Full text

IRBIT Suppresses IP3 Receptor Activity by Competing with IP3 for the Common Binding Site on the IP3 Receptor

Hideaki Ando, Akihiro Mizutani, Hélène Kiefer et al. · Molecular Cell · 2006 · 171 citations · Full text

Molecular Physiology, Signal Transduction, G Protein-coupled Receptor +9