The <i>Caenorhabditis elegans</i> gene <i>unc-76</i> and its human homologs define a new gene family involved in axonal outgrowth and fasciculation

Laird Bloom, H. Robert Horvitz

Proceedings of the National Academy of Sciences

GeneticsMolecular GeneticsCytoskeletonAxon BundlesCellular Neurobiology +17

Fibronectin Regulates Assembly of Actin Filaments and Focal Contacts in Cultured Cells via the Heparin-binding Site in Repeat III₁₃

Laird Bloom, Kenneth C. Ingham, Richard O. Hynes

Molecular Biology of the Cell

Establishing <i>in vitro in vivo</i> correlations to screen monoclonal antibodies for physicochemical properties related to favorable human pharmacokinetics

Lindsay B. Avery, Jason Wade, Mengmeng Wang, +18

mAbs

Immunocytochemical TechniqueImmunologyPathologyImmunotherapyImmunological Biomarkers +19

Antagonists to Human and Mouse Vascular Endothelial Growth Factor Receptor 2 Generated by Directed Protein Evolution In Vitro

E. V. Getmanova, Yan Chen, Laird Bloom, +6

Chemistry & Biology

AngiogenesisDevelopmental BiologySignal TransductionImmunologyEndothelial Dysfunction +7

Development of PF-06671008, a Highly Potent Anti-P-cadherin/Anti-CD3 Bispecific DART Molecule with Extended Half-Life for the Treatment of Cancer

Adam Root, Wei Cao, Bilian Li, +43

Antibodies

Marked antiangiogenic and antitumor efficacy of AG3340 in chemoresistant human non-small cell lung cancer tumors: single agent and combination chemotherapy studies.

David R. Shalinsky, John Brekken, Helen Y. Zou, +5

PubMed

PathologyAntitumor EfficacyTumor BiologySelective Metalloprotease InhibitorCombination Chemotherapy Studies +14

Fundamental Characteristics of the Immunoglobulin VH Repertoire of Chickens in Comparison with Those of Humans, Mice, and Camelids

Leeying Wu, Katarzyna Oficjalska, Matthew Lambert, +11

The Journal of Immunology

Veterinary VaccineGeneticsImmunologyMolecular BiologyImmunogenetics +21

IL-21 Receptor Is Required for the Systemic Accumulation of Activated B and T Lymphocytes in MRL/MpJ-Fas<i>lpr/lpr</i>/J Mice

Andrew L. Rankin, Heath Guay, Deborah Herber, +14

The Journal of Immunology

ImmunologyImmune RegulationIl-21-dependent MannerImmunologic MechanismCd4 T Cell Responses +19

IL-21 Receptor Is Critical for the Development of Memory B Cell Responses

Andrew L. Rankin, Heather MacLeod, Sean Keegan, +7

The Journal of Immunology

Lymphocyte DevelopmentAdaptive Immune SystemHumoral ResponseImmunologyImmune Regulation +20

A Novel GUCY2C-CD3 T-Cell Engaging Bispecific Construct (PF-07062119) for the Treatment of Gastrointestinal Cancers

Divya Mathur, Adam R. Root, Bozena Bugaj‐Gaweda, +24

Clinical Cancer Research