Mie Nakaya

A Family of cAMP-Binding Proteins That Directly Activate Rap1

Hiroaki Kawasaki, Gregory M. Springett, Naoki Mochizuki et al. · Science · 1998 · 1.4K citations

Life Sciences, Biochemistry, Molecular Biology +17

Activation of C3G Guanine Nucleotide Exchange Factor for Rap1 by Phosphorylation of Tyrosine 504

Tamotsu Ichiba, Yuko Hashimoto, Mie Nakaya et al. · Journal of Biological Chemistry · 1999 · 123 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Rap2 as a Slowly Responding Molecular Switch in the Rap1 Signaling Cascade

Yusuke Ohba, Naoki Mochizuki, Keiko Matsuo et al. · Molecular and Cellular Biology · 2000 · 118 citations

Life Sciences, Biochemistry, Molecular Biology +15

Geranylgeraniol Potently Induces Caspase-3-like Activity during Apoptosis in Human Leukemia U937 Cells

Yutaka Masuda, Mie Nakaya, Shigeo Nakajo et al. · Biochemical and Biophysical Research Communications · 1997 · 36 citations

Life Sciences, Oncology, Pharmacology +8

The mechanism of geranylgeraniol-induced apoptosis involves activation, by a caspase-3-like protease, of a c-Jun N-terminal kinase signaling cascade and differs from mechanisms of apoptosis induced by conventional chemotherapeutic drugs

Yutaka Masuda, Mie Nakaya, Toshihiro Aiuchi et al. · Leukemia Research · 2000 · 23 citations

Life Sciences, Cell Biology, Pharmacology +15