Sandlin P. Seguin

Synthesis and Initial Evaluation of YM-08, a Blood-Brain Barrier Permeable Derivative of the Heat Shock Protein 70 (Hsp70) Inhibitor MKT-077, Which Reduces Tau Levels

Yoshinari Miyata, Xiaokai Li, Hsiu-Fang Lee et al. · ACS Chemical Neuroscience · 2013 · 127 citations · Full text

Hsp70 Inhibitors, Molecular Biology, Neurochemical Biomarkers +18

Allosteric Heat Shock Protein 70 Inhibitors Rapidly Rescue Synaptic Plasticity Deficits by Reducing Aberrant Tau

Jose F. Abisambra, Umesh K. Jinwal, Yoshinari Miyata et al. · Biological Psychiatry · 2013 · 105 citations · Full text

Synaptic Plasticity, Protein Function, Molecular Neuroscience +9

Chemical methodology as a source of small-molecule checkpoint inhibitors and heat shock protein 70 (Hsp70) modulators

Donna M. Huryn, Jeffrey L. Brodsky, Kay M. Brummond et al. · Proceedings of the National Academy of Sciences · 2011 · 74 citations

Drug Target, Protein Assembly, Molecular Biology +21

Ciprofloxacin is an inhibitor of the Mcm2-7 replicative helicase

Nicholas W. Simon, Matthew L. Bochman, Sandlin P. Seguin et al. · Bioscience Reports · 2013 · 51 citations · Full text

Inhibition of Simian Virus 40 replication by targeting the molecular chaperone function and ATPase activity of T antigen

Christine Wright, Sandlin P. Seguin, Sheara W. Fewell et al. · Virus Research · 2009 · 41 citations · Full text

Atpase Activity, Viral Replication, Molecular Chaperone Function +8