John K. Simmons

Chemical and structural studies provide a mechanistic basis for recognition of the MYC G-quadruplex

David Calabrese, Xiang Chen, Elena C. Leon et al. · Nature Communications · 2018 · 167 citations · Full text

Medicine, Molecular Biology, Oncology +16

Randomized Phase II Study of Paclitaxel plus Alisertib versus Paclitaxel plus Placebo as Second-Line Therapy for SCLC: Primary and Correlative Biomarker Analyses

Taofeek K. Owonikoko, Huifeng Niu, Kristiaan Nackaerts et al. · Journal of Thoracic Oncology · 2019 · 147 citations · Full text

Medicine, Oncology, Pharmacology +16

Small Molecule Microarrays Enable the Identification of a Selective, Quadruplex-Binding Inhibitor of MYC Expression

Kenneth M. Felsenstein, Lindsey B. Saunders, John K. Simmons et al. · ACS Chemical Biology · 2015 · 125 citations · Full text

Life Sciences, Molecular Biology, Oncology +17

Characterization of tumor mutation burden, PD-L1 and DNA repair genes to assess relationship to immune checkpoint inhibitors response in metastatic renal cell carcinoma

Matthew Labriola, Jason Zhu, Rajan T. Gupta et al. · Journal for ImmunoTherapy of Cancer · 2020 · 100 citations · Full text

Medicine, Immunology, Oncology +17

Generic Protocols for the Analytical Validation of Next-Generation Sequencing-Based ctDNA Assays: A Joint Consensus Recommendation of the BloodPAC’s Analytical Variables Working Group

James H. Godsey, Angela Silvestro, J. Carl Barrett et al. · Clinical Chemistry · 2020 · 96 citations · Full text

Medicine, Hematology, Oncology +17