Ellen van der Aar

Discovery of 2-[[2-Ethyl-6-[4-[2-(3-hydroxyazetidin-1-yl)-2-oxoethyl]piperazin-1-yl]-8-methylimidazo[1,2- <i>a</i> ]pyridin-3-yl]methylamino]-4-(4-fluorophenyl)thiazole-5-carbonitrile (GLPG1690), a First-in-Class Autotaxin Inhibitor Undergoing Clinical Evaluation for the Treatment of Idiopathic Pulmonary Fibrosis

Nicolas Desroy, Christopher Housseman, Xavier Bock et al. · Journal of Medicinal Chemistry · 2017 · 135 citations · Full text

Discovery, Structure–Activity Relationship, and Binding Mode of an Imidazo[1,2-<i>a</i>]pyridine Series of Autotaxin Inhibitors

Agnès Joncour, Nicolas Desroy, Christopher Housseman et al. · Journal of Medicinal Chemistry · 2017 · 59 citations · Full text

Discovery of<i>N</i>-(3-Carbamoyl-5,5,7,7-tetramethyl-5,7-dihydro-4<i>H</i>-thieno[2,3-<i>c</i>]pyran-2-yl)-l<i>H</i>-pyrazole-5-carboxamide (GLPG1837), a Novel Potentiator Which Can Open Class III Mutant Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Channels to a High Extent

Steven E. Van der Plas, Hans Kelgtermans, Tom De Munck et al. · Journal of Medicinal Chemistry · 2017 · 58 citations · Full text

UNBS5162, a Novel Naphthalimide That Decreases CXCL Chemokine Expression in Experimental Prostate Cancers

Tatjana Mijatovic, Tina Mahieu, Céline Bruyère et al. · Neoplasia · 2008 · 52 citations · Full text

Identification of a 4-(Hydroxymethyl)diarylhydantoin as a Selective Androgen Receptor Modulator

F. Nique, Séverine Hebbe, Nicolas Triballeau et al. · Journal of Medicinal Chemistry · 2012 · 51 citations