Daniel D. Coovert

The survival motor neuron protein in spinal muscular atrophy

Daniel D. Coovert · Human Molecular Genetics · 1997 · 708 citations

SMNΔ7, the major product of the centromeric survival motor neuron (SMN2) gene, extends survival in mice with spinal muscular atrophy and associates with full-length SMN

Thanh T. Le, Lan T. Pham, Matthew E.R. Butchbach et al. · Human Molecular Genetics · 2005 · 588 citations · Full text

Valproic acid increases SMN levels in spinal muscular atrophy patient cells

Charlotte J. Sumner, Thanh N. Huynh, Jennifer A. Markowitz et al. · Annals of Neurology · 2003 · 287 citations

Valproic Acid, Molecular Physiology, Spinal Cord Injury +12

Indoprofen Upregulates the Survival Motor Neuron Protein through a Cyclooxygenase-Independent Mechanism

Mitchell R. Lunn, David E. Root, Allison M. Martino et al. · Chemistry & Biology · 2004 · 159 citations · Full text

Cyclooxygenase-independent Mechanism, Medicine, Cell Death +10

Diverse small-molecule modulators of SMN expression found by high-throughput compound screening: early leads towards a therapeutic for spinal muscular atrophy

Jill Jarecki, Xiaocun Chen, Alexandra Bernardino et al. · Human Molecular Genetics · 2005 · 150 citations

Molecular Biology, Smn2 Promoter Activity, Gene Characterization +20