Sonam Parakh

ALS-Associated TDP-43 Induces Endoplasmic Reticulum Stress, Which Drives Cytoplasmic TDP-43 Accumulation and Stress Granule Formation

Adam K. Walker, Kai Y. Soo, Vinod Sundaramoorthy et al. · PLoS ONE · 2013 · 181 citations · Full text

Cell Death, Neurochemical Biomarkers, Er Stress +24

Impaired NHEJ repair in amyotrophic lateral sclerosis is associated with TDP-43 mutations

Anna Konopka, Donna R. Whelan, Md Shafi Jamali et al. · Molecular Neurodegeneration · 2020 · 113 citations · Full text

Rab1-dependent ER–Golgi transport dysfunction is a common pathogenic mechanism in SOD1, TDP-43 and FUS-associated ALS

Kai Y. Soo, Mark A. Halloran, Vinod Sundaramoorthy et al. · Acta Neuropathologica · 2015 · 111 citations

Neurodegenerative Diseases, Amyotrophic Lateral Sclerosis, Common Pathogenic Mechanism +9

Amyotrophic lateral sclerosis-linked UBQLN2 mutants inhibit endoplasmic reticulum to Golgi transport, leading to Golgi fragmentation and ER stress

Mark A. Halloran, Audrey Ragagnin, Marta Vidal et al. · Cellular and Molecular Life Sciences · 2019 · 39 citations · Full text

Amyotrophic Lateral Sclerosis, Signal Transduction, Secretory Pathway +9

The Redox Activity of Protein Disulfide Isomerase Inhibits ALS Phenotypes in Cellular and Zebrafish Models

Sonam Parakh, Sina Shadfar, Emma R. Perri et al. · iScience · 2020 · 36 citations · Full text