Dorota D. Klysz

Transient rest restores functionality in exhausted CAR-T cells through epigenetic remodeling

Evan W. Weber, Kevin R. Parker, Elena Sotillo et al. · Science · 2021 · 558 citations · Full text

Glutamine-dependent α-ketoglutarate production regulates the balance between T helper 1 cell and regulatory T cell generation

Dorota D. Klysz, Xuguang Tai, Philippe A. Robert et al. · Science Signaling · 2015 · 483 citations

Adaptive Immune System, T-regulatory Cell, Immunology +20

Glucose and Glutamine Metabolism Regulate Human Hematopoietic Stem Cell Lineage Specification

Leal Oburoglu, Saverio Tardito, Vanessa Fritz et al. · Cell stem cell · 2014 · 278 citations · Full text

Developmental Biology, Medicine, Stem Cell Mobilization +8

Co-opting signalling molecules enables logic-gated control of CAR T cells

Aidan M. Tousley, Maria Caterina Rotiroti, Louai Labanieh et al. · Nature · 2023 · 251 citations · Full text

Car T Cells, Signal Transduction, Cell Control +9

Delivery of CAR-T cells in a transient injectable stimulatory hydrogel niche improves treatment of solid tumors

Abigail K. Grosskopf, Louai Labanieh, Dorota D. Klysz et al. · Science Advances · 2022 · 220 citations · Full text

Cell Therapy, Engineering, Solid Tumors +22