Harald App

Raf-1 activates MAP kinase-kinase

John Kyriakis, Harald App, Xianfeng Zhang et al. · Nature · 1992 · 1.3K citations

Signal Transduction, Molecular Physiology, Signaling Pathway +5

Synthesis and Biological Evaluations of 3-Substituted Indolin-2-ones:  A Novel Class of Tyrosine Kinase Inhibitors That Exhibit Selectivity toward Particular Receptor Tyrosine Kinases

Li Sun, Ngoc Quang Tran, Flora Tang et al. · Journal of Medicinal Chemistry · 1998 · 486 citations · Full text

Medicinal Chemistry, Pharmaceutical Chemistry, Biochemistry +14

Flk-1 as a target for tumor growth inhibition.

L M Strawn, Gerald McMahon, Harald App et al. · PubMed · 1996 · 318 citations

Endothelial Cells, Cancer Biology, Tumor Biology +18

Tyrphostins. 5. Potent Inhibitors of Platelet-Derived Growth Factor Receptor Tyrosine Kinase:  Structure−Activity Relationships in Quinoxalines, Quinolines, and Indole Tyrphostins

Aviv Gazit, Harald App, Gerald McMahon et al. · Journal of Medicinal Chemistry · 1996 · 227 citations · Full text

Pharmaceutical Science, Indole Tyrphostins, Pharmacotherapy +19

Interleukin 2 induces tyrosine phosphorylation and activation of p72-74 Raf-1 kinase in a T-cell line.

Benjamin L. Turner, Ulf R. Rapp, Harald App et al. · Proceedings of the National Academy of Sciences · 1991 · 164 citations · Full text

T-regulatory Cell, Immunology, Immune Regulation +19