Inhibition of acute lymphoblastic leukaemia by a Jak-2 inhibitor

Naftaly Meydan, T Grunberger, Harjit Dadi, +9

Nature

Hematological MalignancyMalignant Blood DisorderImmunologyHematologyMedicine +2

Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells

Roy Garcia, Tammy Bowman, Guilian Niu, +12

Oncogene

Signal TransductionSignaling PathwayCell RegulationConstitutive ActivationReceptor Tyrosine Kinase +12

Tyrphostins I: synthesis and biological activity of protein tyrosine kinase inhibitors

Aviv Gazit, Pnina Yaish, Chaim Gilon, +1

Journal of Medicinal Chemistry

Blocking of EGF-Dependent Cell Proliferation by EGF Receptor Kinase Inhibitors

Pnina Yaish, Aviv Gazit, Chaim Gilon, +1

Science

Medicinal ChemistryEpidermal Growth FactorChemoprevention StrategyMedicineReceptor Tyrosine Kinase +13

Crystal Structure of Hck in Complex with a Src Family–Selective Tyrosine Kinase Inhibitor

Thomas H. Schindler, Frank Sicheri, Alexander R. Pico, +3

Molecular Cell

Crystal StructureBiochemistryNatural SciencesReceptor Tyrosine KinaseProtein X-ray Crystallography +4

Drug resistance of human glioblastoma cells conferred by a tumor-specific mutant epidermal growth factor receptor through modulation of Bcl-X _L and caspase-3-like proteases

Motoo Nagane, Alexander Levitzki, Aviv Gazit, +2

Proceedings of the National Academy of Sciences

Prevention of Lipopolysaccharide-Induced Lethal Toxicity by Tyrosine Kinase Inhibitors

Abraham Novogrodsky, Alexey Vanichkin, Miriam Patya, +3

Science

ImmunologyCell DeathCellular PharmacologyPharmacotherapyImmune System +19

Flk-1 as a target for tumor growth inhibition.

L M Strawn, Gerald McMahon, Harald App, +15

PubMed

Endothelial CellsCancer BiologyTumor BiologyAngiogenesisReceptor Tyrosine Kinase +16

Tyrphostins Inhibit Epidermal Growth Factor (EGF)-Receptor Tyrosine Kinase Activity in Living Cells and EGF-Stimulated Cell Proliferation

R. Lyall, Asher Zilberstein, Aviv Gazit, +3

Journal of Biological Chemistry

Living CellsSignal TransductionSignaling PathwayGrowth FactorMedicine +13

Selective platelet-derived growth factor receptor kinase blockers reverse sis-transformation.

Marina Kovalenko, Aviv Gazit, Annette Böhmer, +6

PubMed

ThrombosisSignal TransductionAngiogenesisBlood PlateletMedicine +13