John R. MacDougall

Establishment and Characterization of First Trimester Human Trophoblast Cells with Extended Lifespan

Charles H. Graham, Teresa S. Hawley, John R. MacDougall et al. · Experimental Cell Research · 1993 · 1.1K citations

Life Sciences, Cell Biology, Developmental Biology +13

PI3K-δ and PI3K-γ Inhibition by IPI-145 Abrogates Immune Responses and Suppresses Activity in Autoimmune and Inflammatory Disease Models

David G. Winkler, Jonathan P. DiNitto, Janid A. Ali et al. · Chemistry & Biology · 2013 · 258 citations

Life Sciences, Immunology, Pathology +15

Discovery of a Potent and Orally Active Hedgehog Pathway Antagonist (IPI-926)

Martin Tremblay, André Lescarbeau, Michael J. Grogan et al. · Journal of Medicinal Chemistry · 2009 · 251 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

CR011, a fully human monoclonal antibody-auristatin E conjugate, for the treatment of melanoma.

Kam Fai Tse, Michael Jeffers, Vincent A. Pollack et al. · Clinical Cancer Research · 2006 · 187 citations

Medicine, Immunology, Oncology +17

Matrix metalloproteinase-3–dependent generation of a macrophage chemoattractant in a model of herniated disc resorption

Hirotaka Haro, Howard C. Crawford, Barbara Fingleton et al. · Journal of Clinical Investigation · 2000 · 182 citations · Full text

Life Sciences, Cell Biology, Immunology +17