Mutations in a novel gene lead to kidney tumors, lung wall defects, and benign tumors of the hair follicle in patients with the Birt-Hogg-Dubé syndrome

Michael L. Nickerson, Michelle B. Warren, Jorge R. Toro, +17

Cancer Cell

Birt-hogg-dubé SyndromeGenetic DisorderGeneticsPathologyHair Follicle +2

Mutations in the Fumarate Hydratase Gene Cause Hereditary Leiomyomatosis and Renal Cell Cancer in Families in North America

Jorge R. Toro, Michael L. Nickerson, Ming-Hui Wei, +14

The American Journal of Human Genetics

UrologyNorth AmericaMedicineGeneticsPathology +4

Folliculin encoded by the <i>BHD</i> gene interacts with a binding protein, FNIP1, and AMPK, and is involved in AMPK and mTOR signaling

Masaya Baba, Seung‐Beom Hong, Nirmala Sharma, +14

Proceedings of the National Academy of Sciences

Germline BHD-Mutation Spectrum and Phenotype Analysis of a Large Cohort of Families with Birt-Hogg-Dubé Syndrome

Laura S. Schmidt, Michael L. Nickerson, Michelle B. Warren, +12

The American Journal of Human Genetics

Phenotype AnalysisMendelian DisorderBirt-hogg-dubé SyndromeGenetic DisorderGenetics +8

A Gonococcal Efflux Pump System Enhances Bacterial Survival in a Female Mouse Model of Genital Tract Infection

Ann E. Jerse, Nirmala Sharma, Amy N. Simms, +3

Infection and Immunity

Wnt4 induces nephronic tubules in metanephric mesenchyme by a non-canonical mechanism

Shunsuke Tanigawa, Honghe Wang, Yili Yang, +6

Developmental Biology

Metanephric MesenchymeMolecular PhysiologyDevelopmental BiologySignal TransductionSignaling Pathway +8

Hepatic vascular tumors, angiectasis in multiple organs, and impaired spermatogenesis in mice with conditional inactivation of the VHL gene.

Wenbin Ma, Lino Tessarollo, Seung‐Beom Hong, +12

PubMed

SpermatogenesisImmunologyPathologyCell ProliferationVon Hippel-lindau +22

Selective In Vitro Propagation of Nephron Progenitors Derived from Embryos and Pluripotent Stem Cells

Shunsuke Tanigawa, Atsuhiro Taguchi, Nirmala Sharma, +2

Cell Reports

Non-canonical Wnt5a/Ror2 signaling regulates kidney morphogenesis by controlling intermediate mesoderm extension

Kangsun Yun, Rieko Ajima, Nirmala Sharma, +5

Human Molecular Genetics

Non-canonical Wnt5a/ror2Bilateral Duplex KidneyRenal InflammationOrgan DevelopmentCellular Physiology +16

STAT1 activation regulates proliferation and differentiation of renal progenitors

Honghe Wang, Yili Yang, Nirmala Sharma, +5

Cellular Signalling

Stat1 ActivationMedicineCell BiologyCell SignalingKidney Research