Divesh Aidasani

Selective Class I Phosphoinositide 3-Kinase Inhibitors: Optimization of a Series of Pyridyltriazines Leading to the Identification of a Clinical Candidate, AMG 511

Mark H. Norman, Kristin L. Andrews, Yunxin Bo et al. · Journal of Medicinal Chemistry · 2012 · 50 citations · Full text

Chemoprevention Strategy, Molecular Biology, Clinical Candidate +19

Sequential Metabolism of AMG 487, a Novel CXCR3 Antagonist, Results in Formation of Quinone Reactive Metabolites That Covalently Modify CYP3A4 Cys239 and Cause Time-Dependent Inhibition of the Enzyme

Kirk R. Henne, Thuy Tran, Brooke M. VandenBrink et al. · Drug Metabolism and Disposition · 2012 · 41 citations · Full text

In Vitro Drug-Drug Interaction Screens for Canine Veterinary Medicines: Evaluation of Cytochrome P450 Reversible Inhibition

Divesh Aidasani, Matthew J. Zaya, Phyllis B. Malpas et al. · Drug Metabolism and Disposition · 2008 · 35 citations

Substrate Redox Potential Controls Superoxide Production Kinetics in the Cytochrome <i>bc</i> Complex

Jonathan L. Cape, Divesh Aidasani, David Kramer et al. · Biochemistry · 2009 · 15 citations · Full text

Bioelectrochemistry, Molecular Biology, Chemical Biology +17