Tumour DDR1 promotes collagen fibre alignment to instigate immune exclusion

Xiujie Sun, Bogang Wu, Huai-Chin Chiang, +28

Nature

Tumor BiologyMedicineImmunologyImmunoeditingPathology +8

Nasal delivery of an IgM offers broad protection from SARS-CoV-2 variants

Zhiqiang Ku, Xuping Xie, Paul R. Hinton, +22

Nature

VaccinationMucosal VaccinationSars-cov-2 VariantsVaccine TargetImmunology +5

Shikonin inhibits prostate cancer cells metastasis by reducing matrix metalloproteinase-2/-9 expression via AKT/mTOR and ROS/ERK1/2 pathways

Yongqiang Chen, Lu Zheng, Junquan Liu, +4

International Immunopharmacology

Shikonin InhibitsUrologyMatrix Metalloproteinase-2/-9 ExpressionAnti-cancer AgentCancer Cells +6

Characterization of Two Endo-β-1, 4-Xylanases from Myceliophthora thermophila and Their Saccharification Efficiencies, Synergistic with Commercial Cellulase

Abdul Basit, Junquan Liu, Ting Miao, +4

Frontiers in Microbiology

The enhanced effect of lupeol on the destruction of gastric cancer cells by NK cells

Xiaoting Wu, Junquan Liu, Xiaoting Lu, +5

International Immunopharmacology

Gastric Cancer CellsEnhanced EffectChemoprevention StrategyMedicineImmunology +8

Novel β-mannanase/GLP-1 fusion peptide high effectively ameliorates obesity in a mouse model by modifying balance of gut microbiota

Yan Wang, Nuraliya Ablimit, Yunpeng Zhang, +9

International Journal of Biological Macromolecules

ObesityDysbiosisBiochemistryHost-microbe InteractionsGut Microbiota +8

A highly selective humanized DDR1 mAb reverses immune exclusion by disrupting collagen fiber alignment in breast cancer

Junquan Liu, Huai-Chin Chiang, Wei Xiong, +12

Journal for ImmunoTherapy of Cancer

Artesunate enhances γδ T-cell-mediated antitumor activity through augmenting γδ T-cell function and reversing immune escape of HepG2 cells

Qian Peng, Zhang Yong-wen, Zhong-Hai Zhou, +6

Immunopharmacology and Immunotoxicology

Wnt pathway activator TWS119 enhances the proliferation and cytolytic activity of human γδT cells against colon cancer

Yongqiang Chen, Lu Zheng, Mohanad Aldarouish, +5

Experimental Cell Research

Tumor BiologyCytolytic ActivityMedicineCancer Cell BiologyColorectal Cancer +7

Bacterial magnetosomes loaded with doxorubicin and transferrin improve targeted therapy of hepatocellular carcinoma

Jiaojiao Wang, Yuanyuan Geng, Yunpeng Zhang, +6

Nanotheranostics