Jian-Qiao Gu

Combinatorial biosynthesis of novel antibiotics related to daptomycin

Kien T. Nguyen, Daniel Ritz, Jian-Qiao Gu et al. · Proceedings of the National Academy of Sciences · 2006 · 285 citations · Full text

Novel Lipopeptides, Bioorganic Chemistry, Engineering +17

Genetically Engineered Lipopeptide Antibiotics Related to A54145 and Daptomycin with Improved Properties

Kien T. Nguyen, Xiaowei He, Dylan C. Alexander et al. · Antimicrobial Agents and Chemotherapy · 2010 · 110 citations · Full text

Improved Properties, Pulmonary Surfactant, Engineering +17

Non-ribosomal peptide synthetase module fusions to produce derivatives of daptomycin in Streptomyces roseosporus

Sascha Doekel, Marie-Françoise Coëffet-Le Gal, Jian-Qiao Gu et al. · Microbiology · 2008 · 89 citations

Bioorganic Chemistry, Engineering, Molecular Biology +19

Production of novel lipopeptide antibiotics related to A54145 by Streptomyces fradiae mutants blocked in biosynthesis of modified amino acids and assignment of lptJ, lptK and lptL gene functions

Dylan C. Alexander, Jessica L. Rock, Jian-Qiao Gu et al. · The Journal of Antibiotics · 2010 · 42 citations · Full text

Lptl Gene Functions, Biosynthesis, Amino Acids +11

Structural Characterization of Daptomycin Analogues A21978C_1-3(<scp>d</scp>-Asn₁₁) Produced by a Recombinant <i>Streptomyces roseosporus</i> Strain

Jian-Qiao Gu, Kien T. Nguyen, Chhayal Gandhi et al. · Journal of Natural Products · 2007 · 36 citations

Structural Characterization, Antibiotic Adjuvant, Staphylococcus Aureus +19