Systematic identification of genomic markers of drug sensitivity in cancer cells

Mathew J. Garnett, Elena J. Edelman, Sonja J. Heidorn, +51

Nature

Systematic IdentificationGenomic MarkersEngineeringTumor HeterogeneityMedicine +10

Genomic Landscape of Ewing Sarcoma Defines an Aggressive Subtype with Co-Association of <i>STAG2</i> and <i>TP53</i> Mutations

Franck Tirode, Didier Surdez, Xiaotu Ma, +19

Cancer Discovery

Heterogeneity of neuroblastoma cell identity defined by transcriptional circuitries

Valentina Boeva, Caroline Louis‐Brennetot, Agathe Peltier, +25

Nature Genetics

Neuro-oncologyLineage PlasticityDevelopmental BiologyNeuroblastoma Cell IdentityCell Biology +4

Locoregionally administered B7-H3-targeted CAR T cells for treatment of atypical teratoid/rhabdoid tumors

Johanna Theruvath, Elena Sotillo, Christopher Mount, +27

Nature Medicine

Cancer ImmunosurveillanceMedicineImmunologyCell TransplantationCancer Treatment +6

DNA methylation heterogeneity defines a disease spectrum in Ewing sarcoma

Nathan C. Sheffield, Gaëlle Pierron, Johanna Klughammer, +35

Nature Medicine

ChromatinSomatic VariantTumor HeterogeneityEpigenetic ChangeGenetics +8

Chimeric EWSR1-FLI1 regulates the Ewing sarcoma susceptibility gene EGR2 via a GGAA microsatellite

Thomas G. P. Grünewald, Virginie Bernard, Pascale Gilardi‐Hebenstreit, +29

Nature Genetics

Chimeric Ewsr1-fli1MedicinePathologyCancer GenomicsGgaa Microsatellite +6

Multimodal analysis of cell-free DNA whole-genome sequencing for pediatric cancers with low mutational burden

Peter Peneder, Adrian M. Stütz, Didier Surdez, +33

Nature Communications

Clonally Expanded T Cells Reveal Immunogenicity of Rhabdoid Tumors

Amaury Leruste, Jimena Tosello, Rodrigo Nalio Ramos, +28

Cancer Cell

Cancer ImmunosurveillanceRhabdoid TumorsImmunologyTumor ImmunityImmunotherapy +2

Transcriptional Programs Define Intratumoral Heterogeneity of Ewing Sarcoma at Single-Cell Resolution

Marie-Ming Aynaud, Olivier Mirabeau, Nadège Gruel, +19

Cell Reports

Single-cell ResolutionCancer BiologyTumor BiologyEwing SarcomaOncology +14

The occurrence of intracranial rhabdoid tumours in mice depends on temporal control of Smarcb1 inactivation

Zhi‐Yan Han, Wilfrid Richer, Paul Fréneaux, +16

Nature Communications