The Proinflammatory CD14+CD16+DR++ Monocytes Are a Major Source of TNF

Kai-Uwe Belge, Farshid Dayyani, Alexia Horelt, +5

The Journal of Immunology

Immune RegulationImmunologyPathologyImmune SystemProinflammatory Cd14+cd16+dr++ Monocytes +15

Adoptive tumor therapy with T lymphocytes enriched through an IFN-γ capture assay

Christian Becker, Heike Pohla, Bernhard Frankenberger, +4

Nature Medicine

Adoptive Tumor TherapyTumor ImmunologyCell TherapyCancer ImmunosurveillanceImmunology +12

Generation of clinical grade dendritic cells with capacity to produce biologically active IL-12p70

Anke Zobywalski, Miran Javorovic, Bernhard Frankenberger, +4

Journal of Translational Medicine

Prostate cancer lesions are surrounded by FOXP3+, PD-1+ and B7-H1+ lymphocyte clusters

Kathleen Ebelt, Gregor Babaryka, Bernhard Frankenberger, +4

European Journal of Cancer

Perineural InvasionGenitourinary CancerMedicineB7-h1+ Lymphocyte ClustersPathology +5

Humanized tumor mice—A new model to study and manipulate the immune response in advanced cancer therapy

Anja K. Wege, Wolfgang Ernst, Judith Eckl, +6

International Journal of Cancer

Cell TherapyLymphocyte DevelopmentImmunologyImmune RegulationImmunoediting +22

MHC-restricted fratricide of human lymphocytes expressing survivin-specific transgenic T cell receptors

Matthias Leisegang, Susanne Wilde, Stefani Spranger, +4

Journal of Clinical Investigation

Dendritic cells pulsed with RNA encoding allogeneic MHC and antigen induce T cells with superior antitumor activity and higher TCR functional avidity

Susanne Wilde, Daniel Sommermeyer, Bernhard Frankenberger, +7

Blood

Generation of Th1-Polarizing Dendritic Cells Using the TLR7/8 Agonist CL075

Stefani Spranger, Miran Javorovic, Maja Bürdek, +7

The Journal of Immunology

T-regulatory CellImmunologyImmune RegulationImmunologic MechanismInnate Immunity +20

TCR-transgenic lymphocytes specific for HMMR/Rhamm limit tumor outgrowth in vivo

Stefani Spranger, Irmela Jeremias, Susanne Wilde, +7

Blood

All Trans-Retinoic Acid Selectively Down-Regulates Matrix Metalloproteinase-9 (MMP-9) and Up-Regulates Tissue Inhibitor of Metalloproteinase-1 (TIMP-1) in Human Bronchoalveolar Lavage Cells

Marion Frankenberger, R. Hauck, Bernhard Frankenberger, +4

Molecular Medicine