Sophie Giorgetti‐Peraldi

The antidiabetic drug metformin exerts an antitumoral effect in vitro and in vivo through a decrease of cyclin D1 level

Issam Ben Sahra, Kathiane Laurent, Agnès Loubat et al. · Oncogene · 2008 · 847 citations · Full text

Cyclin D1 Level, Antidiabetic Drug Metformin, Antitumoral Effect +8

Metformin, Independent of AMPK, Induces mTOR Inhibition and Cell-Cycle Arrest through REDD1

Isaam Ben Sahra, Claire Regazzetti, Guillaume Robert et al. · Cancer Research · 2011 · 611 citations

Insulin Stimulates Hypoxia-inducible Factor 1 through a Phosphatidylinositol 3-Kinase/Target of Rapamycin-dependent Signaling Pathway

Caroline Treins, Sophie Giorgetti‐Peraldi, Joseph Murdaca et al. · Journal of Biological Chemistry · 2002 · 532 citations · Full text

Targeting Cancer Cell Metabolism: The Combination of Metformin and 2-Deoxyglucose Induces p53-Dependent Apoptosis in Prostate Cancer Cells

Issam Ben Sahra, Kathiane Laurent, Sandy Giuliano et al. · Cancer Research · 2010 · 522 citations

Chemoprevention Strategy, Apoptosis, Cancer Cell Metabolism +16

Hypoxia Decreases Insulin Signaling Pathways in Adipocytes

Claire Regazzetti, Pascal Peraldi, Thierry Grémeaux et al. · Diabetes · 2008 · 276 citations · Full text