Synthesis, Radiosynthesis, and Biological Evaluation of Carbon-11 and Fluorine-18 Labeled Reboxetine Analogues: Potential Positron Emission Tomography Radioligands for in Vivo Imaging of the Norepinephrine Transporter

Fanxing Zeng, Ji-Young Mun, Nachwa Jarkas, +8

Journal of Medicinal Chemistry

Carbon-11 HOMADAM: A novel PET radiotracer for imaging serotonin transporters

Nachwa Jarkas, John R. Votaw, Ronald J. Voll, +8

Nuclear Medicine and Biology

Positron Emission TomographyEngineeringMedicineBiomedical ImagingTheranostics +7

Synthesis, Radiosynthesis, and Biological Evaluation of Carbon-11 Labeled 2β-Carbomethoxy-3β-(3‘-((<i>Z</i>)-2-haloethenyl)phenyl)nortropanes:  Candidate Radioligands for in Vivo Imaging of the Serotonin Transporter with Positron Emission Tomography

Jeffrey S. Stehouwer, Nachwa Jarkas, Fanxing Zeng, +5

Journal of Medicinal Chemistry

Compartmental Modeling of¹¹C-HOMADAM Binding to the Serotonin Transporter in the Healthy Human Brain

Jonathon A. Nye, John R. Votaw, Nachwa Jarkas, +6

Journal of Nuclear Medicine

Development of SPECT imaging agents for the norepinephrine transporters: [123I]INER

Gilles Tamagnan, Éric Brenner, David Alagille, +10

Bioorganic & Medicinal Chemistry Letters

EngineeringImaging AgentTheranosticsRadiopharmaceutical TherapyNorepinephrine Transporters +4

Synthesis, in Vitro Characterization, and Radiolabeling of <i>N</i>,<i>N</i>-Dimethyl-2-(2‘-amino-4‘-substituted-phenylthio)benzylamines:  Potential Candidates as Selective Serotonin Transporter Radioligands

Nachwa Jarkas, Jonathan McConathy, Ronald J. Voll, +1

Journal of Medicinal Chemistry

Molecular PharmacologyMedicinal ChemistryVitro CharacterizationSert AffinityPotential Candidates +13

Synthesis and characterization of EADAM: a selective radioligand for mapping the brain serotonin transporters by positron emission tomography

Nachwa Jarkas, Jonathan McConathy, John R. Votaw, +7

Nuclear Medicine and Biology

Positron Emission TomographyOptogeneticsBrain Serotonin TransportersEngineeringSelective Radioligand +7

Synthesis and In Vivo Evaluation of Halogenated <i>N</i>,<i>N</i>-Dimethyl-2-(2′-amino-4′-hydroxymethylphenylthio)benzylamine Derivatives as PET Serotonin Transporter Ligands

Nachwa Jarkas, Ronald J. Voll, Larry Williams, +3

Journal of Medicinal Chemistry

Synthesis, in vitro characterization, and radiolabeling of reboxetine analogs as potential PET radioligands for imaging the norepinephrine transporter

Fanxing Zeng, Nachwa Jarkas, Jeffrey S. Stehouwer, +5

Bioorganic & Medicinal Chemistry

Positron Emission TomographyEngineeringMedicineReboxetine AnalogsImaging Agent +9

Synthesis, Radiosynthesis, and Biological Evaluation of Fluorine-18-Labeled 2β-Carbo(fluoroalkoxy)-3β-(3′-((<i>Z</i>)-2-haloethenyl)phenyl)nortropanes: Candidate Radioligands for In Vivo Imaging of the Serotonin Transporter with Positron Emission Tomography

Jeffrey S. Stehouwer, Nachwa Jarkas, Fanxing Zeng, +8

Journal of Medicinal Chemistry

Imaging AgentSynaptic TransmissionNeurotransmitterExperimental PharmacologyPeak Uptake +22