Frédérick A. Mallette

mTOR as a central regulator of lifespan and aging

David Papadopoli, Karine Boulay, Lawrence Kazak et al. · F1000Research · 2019 · 419 citations · Full text

The DNA damage signaling pathway is a critical mediator of oncogene-induced senescence

Frédérick A. Mallette, Marie‐France Gaumont‐Leclerc, Gerardo Ferbeyre · Genes & Development · 2007 · 397 citations · Full text

Dna Damage, Genetics, Apoptosis +17

RNF8‐ and RNF168‐dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites

Frédérick A. Mallette, Francesca Mattiroli, Gaofeng Cui et al. · The EMBO Journal · 2012 · 344 citations · Full text

Neutrophil extracellular traps target senescent vasculature for tissue remodeling in retinopathy

François Binet, Gaël Cagnone, Sergio Crespo‐Garcia et al. · Science · 2020 · 272 citations

Ocular Disease, Immunology, Retinal Therapies +18

Senescence-associated secretory phenotype contributes to pathological angiogenesis in retinopathy

Malika Oubaha, Khalil Miloudi, Agnieszka Dejda et al. · Science Translational Medicine · 2016 · 253 citations