Ultraviolet radiation damages self noncoding RNA and is detected by TLR3

Jamie J. Bernard, Christopher Cowing-Zitron, Teruaki Nakatsuji, +7

Nature Medicine

ChromatinUltraviolet LightNatural SciencesUltraviolet Radiation DamagesMolecular Biology +5

NLRP3/Cryopyrin Is Necessary for Interleukin-1β (IL-1β) Release in Response to Hyaluronan, an Endogenous Trigger of Inflammation in Response to Injury

Kenshi Yamasaki, Jun Muto, Kristen R. Taylor, +8

Journal of Biological Chemistry

ImmunologyImmune RegulationEndogenous TriggerImmune SystemInflammation +16

Staphylococcus epidermidis Antimicrobial δ-Toxin (Phenol-Soluble Modulin-γ) Cooperates with Host Antimicrobial Peptides to Kill Group A Streptococcus

Anna L. Cogen, Kenshi Yamasaki, Jun Muto, +7

PLoS ONE

Microbial PathogensImmunologyPhenol-soluble Modulin-γDermatologyBacterial Pathogens +15

Engagement of CD44 by hyaluronan suppresses TLR4 signaling and the septic response to LPS

Jun Muto, Kenshi Yamasaki, Kristen R. Taylor, +1

Molecular Immunology

InflammationSeptic ResponseCytokineInnate Immune SystemImmune Regulation +8

Hyaluronan digestion controls DC migration from the skin

Jun Muto, Yasuhide Morioka, Kenshi Yamasaki, +5

Journal of Clinical Investigation

Hyal1 ExpressionImmunologyImmunologic MechanismDermatologyImmunotherapy +19

Tissue damage drives co-localization of NF-κB, Smad3, and Nrf2 to direct Rev-erb sensitive wound repair in mouse macrophages

Dawn Z. Eichenfield, Ty D. Troutman, Verena M. Link, +10

eLife

Tlr LigandsInnate Immune SystemImmunologyImmune RegulationInnate Immunity +19

Accumulation of Elafin in Actinic Elastosis of Sun-Damaged Skin: Elafin Binds to Elastin and Prevents Elastolytic Degradation

Jun Muto, Kei Kuroda, Hiroshi Wachi, +2

Journal of Investigative Dermatology

Actinic ElastosisElafin BindsCutaneous BiologySun-damaged SkinCytoskeleton +7

Anti-inflammatory effects of differential molecular weight Hyaluronic acids on UVB-induced calprotectin-mediated keratinocyte inflammation

Liuying Hu, Satoshi Nomura, Yasunari Sato, +6

Journal of Dermatological Science

TSLP Impairs Epidermal Barrier Integrity by Stimulating the Formation of Nuclear IL-33/Phosphorylated STAT3 Complex in Human Keratinocytes

Xiuju Dai, Jun Muto, Ken Shiraishi, +4

Journal of Investigative Dermatology

InflammationSignal TransductionCutaneous BiologyImmunologyImmunologic Mechanism +5

Hyaluronan Breakdown Contributes to Immune Defense against Group A Streptococcus

Nina N. Schommer, Jun Muto, Victor Nizet, +1

Journal of Biological Chemistry