Avraham Shakked

Single-cell analysis uncovers that metabolic reprogramming by ErbB2 signaling is essential for cardiomyocyte proliferation in the regenerating heart

Hessel Honkoop, Dennis E. M. de Bakker, Alla Aharonov et al. · eLife · 2019 · 266 citations · Full text

Cardiac Muscle, Cardiac Progenitor Cells, Cardiac Regeneration +21

ERBB2 drives YAP activation and EMT-like processes during cardiac regeneration

Alla Aharonov, Avraham Shakked, Kfir Baruch Umansky et al. · Nature Cell Biology · 2020 · 216 citations

Cardiac Muscle, Cardiomyopathy, Developmental Biology +12

Small-molecule inhibition of Lats kinases may promote Yap-dependent proliferation in postmitotic mammalian tissues

Nathaniel R. Kastan, Ksenia Gnedeva, Theresa Alisch et al. · Nature Communications · 2021 · 180 citations · Full text

ERK1/2 inhibition promotes robust myotube growth via CaMKII activation resulting in myoblast-to-myotube fusion

Tamar Eigler, Giulia Zarfati, Emmanuel Amzallag et al. · Developmental Cell · 2021 · 101 citations · Full text

An enhancer-based gene-therapy strategy for spatiotemporal control of cargoes during tissue repair

Ruorong Yan, Valentina Cigliola, Kelsey A Oonk et al. · Cell stem cell · 2022 · 61 citations · Full text

Regenerative Medicine, Spatiotemporal Control, Engineering +12