Melanie Kaufholz

Structural and functional analysis of phosphorylation-specific binders of the kinase ERK from designed ankyrin repeat protein libraries

Lutz Kummer, Petra Parizek, Peter Rube et al. · Proceedings of the National Academy of Sciences · 2012 · 100 citations · Full text

PKA-RII subunit phosphorylation precedes activation by cAMP and regulates activity termination

Jörg Isensee, Melanie Kaufholz, Matthias J. Knape et al. · The Journal of Cell Biology · 2018 · 75 citations · Full text

Structure of cyclin G-associated kinase (GAK) trapped in different conformations using nanobodies

A. Chaikuad, Tracy Keates, Cécile Vincke et al. · Biochemical Journal · 2014 · 69 citations · Full text

Crystal Structure, Protein Assembly, Molecular Biology +19

Knowledge-Based Design of a Biosensor to Quantify Localized ERK Activation in Living Cells

Lutz Kummer, Chia-Wen Hsu, Onur Dağliyan et al. · Chemistry & Biology · 2013 · 56 citations · Full text

Signal Transduction, Engineering, Cell Signaling +14

Rp-cAMPS Prodrugs Reveal the cAMP Dependence of First-Phase Glucose-Stimulated Insulin Secretion

Frank Schwede, Oleg G. Chepurny, Melanie Kaufholz et al. · Molecular Endocrinology · 2015 · 38 citations · Full text

Camp Signaling, Insulin Signaling, Gastrointestinal Peptide Hormone +20