Alexander Hruscha

ALS‐associated fused in sarcoma (FUS) mutations disrupt Transportin‐mediated nuclear import

Dorothee Dormann, Ramona Rodde, Dieter Edbauer et al. · The EMBO Journal · 2010 · 817 citations · Full text

Efficient CRISPR/Cas9 genome editing with low off-target effects in zebrafish

Alexander Hruscha, Peter Krawitz, Alexandra Rechenberg et al. · Development · 2013 · 488 citations

Genetics, Molecular Biology, Crispr/cas9 Mutagenesis +18

Loss of ALS-associated TDP-43 in zebrafish causes muscle degeneration, vascular dysfunction, and reduced motor neuron axon outgrowth

Bettina Schmid, Alexander Hruscha, Sebastian Hogl et al. · Proceedings of the National Academy of Sciences · 2013 · 172 citations · Full text

Neurodegenerative Diseases, Protein Function, Amyotrophic Lateral Sclerosis +15

Missense Mutations in the Progranulin Gene Linked to Frontotemporal Lobar Degeneration with Ubiquitin-immunoreactive Inclusions Reduce Progranulin Production and Secretion

Sunita S. Shankaran, Anja Capell, Alexander Hruscha et al. · Journal of Biological Chemistry · 2007 · 168 citations · Full text

<i>In Vivo</i>Imaging of Disease-Related Mitochondrial Dynamics in a Vertebrate Model System

Gabriela Plucińska, Dominik Paquet, Alexander Hruscha et al. · Journal of Neuroscience · 2012 · 101 citations · Full text

Engineering, Cytoskeleton, Mitochondrial Biology +21