Anne L. Ashford

DYRK1A-mediated Cyclin D1 Degradation in Neural Stem Cells Contributes to the Neurogenic Cortical Defects in Down Syndrome

Sònia Najas, Juan Arranz, Pamela A. Lochhead et al. · EBioMedicine · 2015 · 88 citations · Full text

Life Sciences, Developmental Biology, Genetics +17

A novel DYRK1B inhibitor AZ191 demonstrates that DYRK1B acts independently of GSK3β to phosphorylate cyclin D1 at Thr286, not Thr288

Anne L. Ashford, David Oxley, Jason G. Kettle et al. · Biochemical Journal · 2013 · 81 citations

Life Sciences, Molecular Biology, Oncology +17

Identification of DYRK1B as a substrate of ERK1/2 and characterisation of the kinase activity of DYRK1B mutants from cancer and metabolic syndrome

Anne L. Ashford, Tom Dunkley, Mark Cockerill et al. · Cellular and Molecular Life Sciences · 2015 · 34 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17