Pamela A. Lochhead - Concepedia

Author

Pamela A. Lochhead

Babraham Institute ORCID

Also Known As

P A Lochhead, Pamela A Lochhead, Pamela A. LOCHHEAD, Pamela A. Lochhead, Pamela Lochhead, Pamela A. Lochhead

Publications

Citations

H-Index

Concepts

All Affiliations

Babraham Institute University of Dundee Cancer Research UK Scotland Institute MRC Protein Phosphorylation and Ubiquitylation Unit Newcastle University

About

Pamela A. Lochhead is an author at Babraham Institute specializing in medicine, cell biology, and cell signaling.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	11	11	1.5K
2	Cell Biology	10	10	1.4K
3	Natural Sciences	7	7	960
4	Biochemistry	4	4	641
5	Biomolecular Engineering	1	1	14

Pamela A. Lochhead

Publications

1.8K

Citations

H-Index

Page 1

	Year	Citations
5-aminoimidazole-4-carboxamide riboside mimics the effects of insulin on the expression of the 2 key gluconeogenic genes PEPCK and glucose-6-phosphatase. Pamela A. Lochhead, Ian P. Salt, Kay S. Walker, Diabetes Molecular BiologyInsulin SignalingProtein SynthesisG6pase Gene PromotersGene Promoters	2000	391
Activation-Loop Autophosphorylation Is Mediated by a Novel Transitional Intermediate Form of DYRKs Pamela A. Lochhead, Gary Sibbet, Nick Morrice, Cell Activation-loop Autophosphorylation IsSignal TransductionMolecular PhysiologySignaling PathwayReceptor Tyrosine Kinase	2005	318
A Chaperone-Dependent GSK3β Transitional Intermediate Mediates Activation-Loop Autophosphorylation Pamela A. Lochhead, Ross Kinstrie, Gary Sibbet, Molecular Cell Signal TransductionSignaling PathwayNatural SciencesChaperonesCellular Biochemistry	2006	271
Inhibition of GSK-3 Selectively Reduces Glucose-6-Phosphatase and Phosphoenolpyruvate Carboxykinase Gene Expression Pamela A. Lochhead, Matthew P. Coghlan, Simon Q.J. Rice, Diabetes Metabolic RemodelingInsulin SignalingMetabolic SyndromeCell SignalingBasal Gene Expression	2001	215
Activating ROCK1 somatic mutations in human cancer Pamela A. Lochhead, Grant Wickman, Mokdad Mezna, Oncogene Somatic VariantOncogenic AgentRock1 Somatic MutationsCancer GeneticsMedicine	2010	93
DYRK1A-mediated Cyclin D1 Degradation in Neural Stem Cells Contributes to the Neurogenic Cortical Defects in Down Syndrome Sònia Najas, Juan Arranz, Pamela A. Lochhead, EBioMedicine	2015	83
Protein Kinase Activation Loop Autophosphorylation in Cis: Overcoming a Catch-22 Situation Pamela A. Lochhead Science Signaling	2009	79
A novel DYRK1B inhibitor AZ191 demonstrates that DYRK1B acts independently of GSK3β to phosphorylate cyclin D1 at Thr286, not Thr288 Anne L. Ashford, David Oxley, Jason G. Kettle, Biochemical Journal	2013	74
Paradoxical activation of the protein kinase-transcription factor ERK5 by ERK5 kinase inhibitors Pamela A. Lochhead, Julie A. Tucker, Natalie J. Tatum, Nature Communications	2020	45
Characterization of a Domain That Transiently Converts Class 2 DYRKs into Intramolecular Tyrosine Kinases Ross Kinstrie, Nathan Luebbering, Diego Miranda‐Saavedra, Science Signaling	2010	44

Page 1